Senior Biostatistician - Bioinformatics & Biostatistics

Senior Biostatistician

Details of the role: 3 years fixed term, full-time. Working pattern: Monday - Friday.

About us

The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

About the role

In this role you will provide data analysis as part of the Bioinformatics & Biostatistics platform to support to the UCLH-Francis Crick Institute clinical Legacy study , working within UKRI supported PROVAC consortium in partnership with the project leads at the University of Cambridge. PROVAC aims to enhance the SARS-CoV-2 vaccine strain selection process by developing models to predict which variants may emerge in the future and measure immune responses against this potential future evolution. This will enable researchers to choose the variant of the virus to utilise in the next vaccine and provide the best possible future population protection.

You will support analysis of metadata and new experimental data within the PROVAC centralised data repository. Utilising a number of programming, statistical and data analysis techniques, you will analyse data from participants in the UCLH-Crick Legacy study, where their clinical data is linked to a variety of measurements produced by technologies such as the latest high throughput genomic technologies and multi-parameter serological data. A strength of the Legacy study is its rich metadata (including vaccination history, infection episodes), in combination of different laboratory results: nasopharyngeal PCRs, viral sequencing; a suite of serological testing; and increasingly assessment of the cellular responses to infection and vaccination.

What you will be doing

As a Senior Biostatistician in the Bioinformatics & Biostatistics platform at the Crick, you will:

• Work collaboratively across the PROVAC collaboration to co-design experiments, formulate analysis plans and interpret results.
• Perform standard and advanced analyses of high-dimensional, data-intensive and complex research questions across the biomedical research spectrum using bioinformatics, biostatistics, machine learning and AI approaches.
• Empower biologists to understand their datasets, using our broad training portfolio to enable data curiosity and develop analytical skills.
• Design innovative approaches for recurrent and novel projects, and deploy corresponding tools internally, across PROVAC and beyond.

About you

You will bring

• A degree in a relevant subject with an extensive analytical component. E.g., mathematics, biostatistics, epidemiology, bioinformatics, or related fields.
• Advanced proficiency in R or Python programming.
• Experience applying statistical analysis techniques to solve complex data analysis problems in a collaborative biological research environment.
• Experience in data curation, pre-processing, and management especially with large biomedical datasets.
• Experience in running bioinformatics analysis software on an HPC system.
• Basic knowledge of molecular biology.
• Proficiency in data visualisation tools (e.g., ggplot2 in R, Seaborn in Python) to effectively communicate research findings.

To see the complete job description click here .

To see more about team click here .

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture!

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently.

• We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world.

• We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email:

To find out more about life at the Crick click here .

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

• Visas: Applicants for this role will be eligible for sponsorship to work in the UK
• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.

• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.

• Health & Well-being:

• 24/7 GP consultation services.

• Occupational health services and mental health support programs.

• Eye care vouchers and discounted healthcare plans.

• Work-Life Balance:

• Back-up care for dependents.

• Childcare support allowance.

• Annual leave purchase options.
• Crick Networks offering diverse groups' support, community and inclusive social events.

• Perks:

• Discounted gym memberships, bike-to-work scheme, and shopping discounts.

• Subsidised on-site restaurant and social spaces for team interaction.

• Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.

Find out what benefits the Crick has to offer:

For more information on our great pay and benefits package please click here:

Equality, Diversity & Inclusion:

We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.

Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute's success.

The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.

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