Senior Laboratory Research Scientist

Job Title: Senior Laboratory Research Scientist (SLRS) - Schreiber A Lab

Details of the role: Fixed term contract for 1-year, full time. Working pattern: Monday - Friday.

Salary: From £39,950 dependent on skills and experience

Application closing date: 4th March :59GMT

About us

The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We've removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for an enthusiastic and highly motivated researcher with strong expertise in cell biology interested in developing novel more sensitive screening approaches for molecular glue identification to accelerate drug discovery in the targeted protein degradation field. The Schreiber lab is part of the Prosperity Partnership between the Francis Crick Institute, AstraZeneca and Imperial College London which is focused on developing a rule book for the rational discovery of molecular glue degraders. We are studying how autophagy and the ubiquitin proteasome system can be utilized to target a wide range of currently undruggable disease relevant targets (e.g. protein aggregates and damaged mitochondria). The ultimate aim is to unlock novel biology and exploit its revolutionary therapeutic potential.

Dependent on funding, there is potential for this role to be extended after the initial contract term.

What you will be doing

As an SLRS at the Crick, you will:

• Develop and lead your own projects
• Contribute to other projects within the lab on a collaborative basis
• Provide organisational and administrative expertise for this multi-disciplinary lab

About you

You will bring:

• PhD in molecular and/or cellular biology, biochemistry, biophysics or related disciplines, or in the final stages of PhD submission.
• Strong expertise in mammalian cell culture
• Experience in developing quantitative high-throughput screening approaches in cells
• Expertise in studying protein interactions preferably in cells
• Excellent organisational skills, thorough record-keeping and attention to detail
• Good communication, presentation, and data analysis skills

To see the complete job description click here .

To see more about team/Group Leader click here .

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture!

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently.
• We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world.
• We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email:

To find out more about life at the Crick click here .

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

Visas: Applicants for this role will be eligible for sponsorship to work in the UK

Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.

Pension Scheme: Defined contribution pension with employer contributions of up to 16%.

Health & Well-being:

24/7 GP consultation services.

Occupational health services and mental health support programs.

Eye care vouchers and discounted healthcare plans.

Work-Life Balance:

Back-up care for dependents.

Childcare support allowance.

Annual leave purchase options.

Crick Networks offering diverse groups' support, community and inclusive social events.

Perks:

Discounted gym memberships, bike-to-work scheme, and shopping discounts.

Subsidised on-site restaurant and social spaces for team interaction.

Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.